the encysted (factors on what makes them encyst in the colon is unknown), hypobiotic Cyathostomin larvae are largely unaffected by any anthelmintic, this is not due to resistance but rather the encysting physiology. The hypobiotic population makes up 50% of the larval population, which is 90% of the total population (10% adults). For various reasons, larvae emerge in Spring, often many at once (one is a reduction of adults in the lumen). This disease has a PPP of 6-14 weeks if there is no hypobiosis. Most larvae are on the pasture in Autumn.