Megaloblastic Anemia

• Megaloblastic Anemia


  Results from inhibition of DNA synthesis during red blood cell production, continuing cell growth without division
• Megalobastic Anemia are due to B12 or Folic acid deficiency
• Megaloblastic Anemia


  Clinical Manifestations:

  • cracked lips, sore tongue
  • macrocytic, normochromic RBCs

  Lab results:

  • Decreased RBC
  • Decreased hemoglobin
  • Decreased hematocrit
  • increased MCV
  • Increased MCHC
• Megaloblastic Anemia

  Management:

  • Well-balanced diet (green vegetables, liver, organ meats)
  • Folic acid 1 mg/day per orem as prescribed.

  Note: Folic acid deficiency among pregnant clients may cause congenitally acquired neural tube defects. (spina bifida)