KREB'S CYCLE

• WHERE DOES THE KREB'S CYCLE OCCUR?

  mitochondrial matrix
• PROCESS OF THE KREB'S CYCLE?

  1. AcetylCoA #ILOVEJASMINE releases CoA to collect more acetate
  2. Acetyl reacts with 4C sugar
  3. Forming a 6C sugar
  4. 6C sugar is dehydrogenated and decarboxylated
  5. Producing a 5C sugar
  6. 5C sugar is dehydrogenated and decarboxylated to regenerate 4C sugar for start of cycle
  7. ATP is also released while forming 4C sugar
• HOW MANY TIMES DOES THE KREB'S CYCLE OCCUR PER GLUCOSE MOLECULE?

  2
• WHAT ARE THE KREB'S CYCLE PRODUCTS PER GLUCOSE MOLECULE?

  4 CO2, 6 r.NAD, 2 r.FAD, 2 ATP
• WHAT ARE THE KREB'S CYCLE PRODUCTS PER CYCLE?

  2 CO2, 3 r.NAD, 1 r.FAD, 1 ATP
• WHAT IS THE SIGNIFICANCE OF THE KREB'S CYCLE?

  • breaks macromolecules into smaller ones
  • produces hydrogen atoms (carried by NAD to electron transfer chain) to provide energy for oxidative phosphorylation
  • regenerates 4C molecule that combines with acetylCoA
  • source of intermediate compounds used by cell in manufacture of other important substances
• EXAMPLE OF KREB'S CYCLE BREAKING MACROMOLECULES INTO SMALLER ONES?

  pyruvate into carbon dioxide
• WHAT DOES THE PROVIDING OF HYDROGEN ATOMS FOR ENERGY FOR OXIDATIVE PHOSPHORYLATION ALLOW?

  production of ATP, providing metabolic energy
• WHAT HAPPENS IF 4C ISN'T REGENERATED?

  acetylCoA accumulates
• EXAMPLES OF INTERMEDIATE COMPOUNDS USED BY CELL FOR MANUFACTURE AS A RESULT OF KREB'S CYCLE?

  fatty acids, AAs, chlorophyll
• WHAT DOES IT MEAN FOR A SUBSTANCE TO BE DECARBOXYLATED?

  loses one carbon dioxide molecule