Inherit Diseases From Our Family-Polydactyly&Cystic Fibrosis

• What are inherited disorders?


  Conditions that can be passed on through certain alleles from parents
• What are the two examples of inherited disorders discussed in the video?

  Polydactyly and cystic fibrosis
• What is polydactyly?


  A condition where a baby is born with extra fingers or toes
• How is polydactyly inherited?


  It is caused by a dominant allele
• If one parent has the polydactyly allele and the other is normal, what is the probability of having a child with polydactyly?


  50% chance
• What is the genotype of a heterozygous individual with polydactyly?


  One dominant polydactyly allele and one normal allele
• What is cystic fibrosis caused by?


  A recessive allele
• What are the effects of cystic fibrosis on the body?


  It results in thick sticky mucus in various parts of the body, especially the lungs and pancreas
• What is the genotype needed to have cystic fibrosis?


  Two recessive alleles
• What do we call individuals who carry one copy of the cystic fibrosis allele but do not have the condition?


  Carriers
• What is the offspring phenotype ratio when two carriers of cystic fibrosis are crossed?


  3 normal phenotypes to 1 cystic fibrosis phenotype
• What is embryo screening?


  A process to check embryos for genetic disorders before implantation
• What happens if a genetic disorder is found during embryo screening?


  The parents and doctors might decide to discard that embryo
• What are the advantages of embryonic screening?


  • Reduces overall suffering by preventing health problems
  • Saves money on treating genetic disorders
• What are the concerns regarding embryonic screening?


  • Implies people with genetic problems are less desirable
  • Potential future screening for non-health traits (e.g., eye color)
• What is the current legal status of screening for non-health traits in the UK?


  There are laws in place to prevent this