Acute Glomerulonephritis

• Acute Glomerulonephritis 


  Also referred to as Post-streptococcal
• Acute Glomerulonephritis

  True or False: The strep causes the inflammation of the kidney - FALSE
• Acute Glomerulonephritis

  True or False: The antigen-antibody complex that forms due to the strep causes the inflammation - TRUE
• Acute Glomerulonephritis

  Pathology:

  Untreated or recent streptococcal infection - immune system responds by creating antigen-antibody complexes (14 days after infection) - antibodies get lodged in the glomeruli - inflammation and scarring - decreased GFR - FV overload and edema
• Acute Glomerulonephritis

  Signs and symptoms: mnemonic - HAD STREP
• Acute Glomerulonephritis

  Signs and symptoms:

  • Hypertension - dt sodium retention
  • positive Antistreptolysin O (ASO)
  • Decreased GFR
  • Swelling in the face or eyes (edema)
  • Tea-colored or cola-colored urine - dt to azotemia
  • Recent strep infection
  • Elevated labs: Azotemia (increased BUN and crea)
  • mild Proteinuria
• Acute Glomerulonephritis

  Treat underlying cause:

  • Antibiotics - infection
  • Antihypertensives - control BP
  • Diuretics - fluid retention and edema
  • Corticosteroids - inflammation

  Diet: Low sodium, low protein, high carbs