Gottesman - Genetics

• Nature/nurture debate
• Schizophrenia + Bipolar
• 2010 - Aim to investigate the extent children of parents with mental illness develop these illnesses themselves.
• Denmark - National cohort study of 2.7 million people born in Denmark alive in 1968 onwards and 10 years old or more by 2007.
• Sample - 196 couples both hospitalised with schizophrenia by a ICD 8 or 10 diagnosis

  83 couples both hospitalised with bipolar by a ICD 8 or 10 diagnosis

  Not a low sample size as the target population are rare
• Social sensitivity very high - Makes people with these conditions not want to have kids so they don't pass the condition to them
• 196 - 270 children - 27.3% chance + 39.2% schizophrenia related + 7% if only one parent + 0.86% if no parents
• 83 - 146 children - 24.9% chance + 36% negative symptoms + 4.4% one parent + 0.48% if no parents
• Chance of any hospitalised offspring due to their parents conditions:

  Schizophrenia - 67.5%

  Bipolar - 44.2%