Uncontrolled cell division

• what is the effect of drugs on cancer cells?


  reduced rate of mitosis
• Chromosomes line up at the equator attached to spindke fibres..

  In metaphase
• suggest why the development of monopolar mitosis spjndle would prevent successful mitosis

  • no separation of chromatids
  • Chromatids would go to one side
  • Doubled chromosome number in one daughter cell and the other gets no chromosomes
• explain why the student only used the root tip?

  because its where Mitosis occurs
• Why does it have to be thin?

  single layer of cells so light can pass through to make the organelles visible
• The division of cytoplasm is called..

  cytokenisis
• Describe and explain what the student should have done when counting the cells to make sure the mitosis index he obtained was accurate?


  A large number of fields of view to ensure a representative sample
• How does a chemical stop the growth of roots?


  Stops mitosis

  By stopping spindle fibres from forming

  So preventing separation of sister chromatids

  so no new cells added
• Suggest why preventing the formation of spindle fibres could be used for cancer.


  Chromosomes cannot attach to spindle fibres so no mretaphase
• Suggest why the drug could be used even though it affects some healthy cells


  Cancer cells divide uncontrollably
• Evaluate the effectiveness of the drug towards stomach cancer 


  For = stops mitosis so no cell division resulting in the tumour not growing

  Against = healthy cells can be damaged

  The effectiveness and dosage is unknown.