adrenal disease

• Causes of hyperadrenocorticism include…

  • Pituitary dependent (80-90%)
  • Micro and macro adenomas, adenocarcinomas - too much ACTH which is not responding to the negative feedback loop
  • [Subgroup pars intermedia]
  • Adrenal dependent (10-20%)
  • Functional adrenal adenomas and carcinomas (50:50) causing high cortisol
  • Iatrogenic
  • Exogenous steroids
  • [Ectopic ACTH]
• what is produced by the different segments?

  A) catecholamines

  B) glucocorticoids

  C) mineralocorticoids

  D) androgens