Transfusion Teaching Session

• What are the indications for a packed RBC infusion?


  Bleeding

  Anaemia

  Haemoglobin disorders
• What are the indications for platelet transfusions?

  To treat/prevent bleeding in pts with thrombocytopaenia
• What are the indications of fresh frozen plasma (FFP) infusions?

  Bleeding due to multiple clotting factor deficiencies (disseminated intravascular coagulation (DIC))

  Inherited clotting factor deficiencies (Factor V deficiency) where a clotting factor concentrate is not yet available
• What is cryoprecipitate?

  Made from fresh frozen plasma which is frozen & repeatedly thawed in lab to produce concentrated clotting factors (Factor VIII, vWF, fibrinogen)
• What are the indications for cryoprecipitate transfusion?

  Bleeding associated with decreased fibrinogen levels, congenital or acquired dysfibrinogenaemia & DIC
• What are the licensed medicinal products from human plasma donations?

  Human albumin solution

  Clotting factors concentrates/haemophilia products

  Immunoglobulin solutions
• Patients who are not symptomatic should not be transfused.