AO3 - real world application
The menstrual cycle has been the subject of psychological research due to the behavioural changes often linked to it, e.g.- mood swings, irritability.
As a result, improving the understanding of biological rhythms has led to PMS (pre menstrual stress) being considered a psychological event out of an individual's control
This has led to severe PMS being used as a valid defence in major crimes where witnesses have successfully argued that it's akin to a mental disorder sso individuals should not be held responsible for their actions (e.g. Ms English, 1987)