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component 3
immunology and disease
antibodies
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sophie w
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Cards (15)
what are
antibodies
(structurally)
y shaped
globular proteins
what is each antibody molecule made out of
four
polypeptide
chains and two
antigen-binding
sites
what is the antigen-antibody complex
each antibody is
specific
to an antigen
what happens when the
antigen-antibody
complex is formed
they render the antigen
inactive
how do
antibodies
render antigens inactive
by processes such as
agglutination
what is
agglutination
clumping together of
bacteria
how does
agglutination
help
it allows
phagocytes
to locate and engulf
pathogens
what is the top half of the y-shaped globular protein, antibody called
variable region
what is the bottom half of the
y-shaped
globular protein
called
the
constant region
what is the
constant region
of the y-shaped globular protein made of
heavy chains
and
disulphide bridges
what is the
variable region
of the y-shaped globular protein made of
light chains and
disulphide bridges
what's the highest level of protein structure an antibody has
quaternary
what type of bond holds the
polypeptide
chains together between sulfur-containing variable groups
disulfide bridges
explain how the structure of an antibody ensure that only bind to one type of antigen
the
variable region
is only complementary to one type of antigen
how is the structure of an
antibody
adapted to help
agglutination
occur
as there are 2
light chains
the antibody can bind to two
antigen
molecules at once