Stem cells

• -Cells that serve as a normal reservoir for new cells needed to replace damaged or dying cells


  What are stem cells?
• Undifferentiated cells that become the kinds of cells that make up your body and replace old cells when they wear out and die


  Stem cells
• A cell doesn't have a job yet


  Undifferentiated cells
• Already has a specific job to do within the body

  Differentiated cell
• -Found in all people and are used to replace cells in many kinds of tissue as they wear out and die (think bone marrow)

  -Multipotent


  Adult stem cells
• Cell has ability to become several different kinds of cells. More of its DNA has been turned off.


  Multipotent
• -process to artificially form embryonic stem cells by unspecializing a typical somatic cell


  Induced Pluripotent Stem cell
• cloning by nuclear transfer


  Nuclear Transplant Stem cells
• Umbilical cord stem cells/bone marrow/"adult"


  multipotent stem cell
• Can differentiate into most types cell in the body (with the exception of zygote)

  -Embryonic stem cells, induced pluripotent


  Pluripotent
• -Can become any tissue, even the extra-embryonic tissue

  -Ex: fertilized egg


  Totipotent
• -Similar cells found in bone marrow, under skin

  -Tissue specific stem cells have been derived from brain, bone marrow, blood, skeletal muscle, skin, teeth, heart, liver, gut, ovarian epithelium, and testes


  Examples of adult stem cells
• -Regeneration of damaged or lost bone tissue

  - insulin-producing cells to treat diabetes

  -Treatment of bone & blood cancers

  -repair nerve /paralysis/Parkinson's disease

  - Repair of some damaged heart tissue


  Disease possible be helped by stem cells
• Created by iPS (reprogram a somatic cell)

  blastocyts (from extra IVF attempts)


  Source pluripotent Stem cells
• Embryonic


  Which stem cell has the most potential for treating diseases?
• structure that holds embryonic stem cells


  blastocyst inner cell mass

  
• -Cells that serve as a normal reservoir for new cells needed to replace damaged or dying cells


  What are stem cells?
• Undifferentiated cells that become the kinds of cells that make up your body and replace old cells when they wear out and die


  Stem cells
• A cell doesn't have a job yet


  Undifferentiated cells
• Already has a specific job to do within the body

  Differentiated cell
• -Found in all people and are used to replace cells in many kinds of tissue as they wear out and die (think bone marrow)

  -Multipotent


  Adult stem cells
• Cell has ability to become several different kinds of cells. More of its DNA has been turned off.


  Multipotent
• -process to artificially form embryonic stem cells by unspecializing a typical somatic cell


  Induced Pluripotent Stem cell
• cloning by nuclear transfer


  Nuclear Transplant Stem cells
• Umbilical cord stem cells/bone marrow/"adult"


  multipotent stem cell
• Can differentiate into most types cell in the body (with the exception of zygote)

  -Embryonic stem cells, induced pluripotent


  Pluripotent
• -Can become any tissue, even the extra-embryonic tissue

  -Ex: fertilized egg


  Totipotent
• -Similar cells found in bone marrow, under skin

  -Tissue specific stem cells have been derived from brain, bone marrow, blood, skeletal muscle, skin, teeth, heart, liver, gut, ovarian epithelium, and testes


  Examples of adult stem cells
• -Regeneration of damaged or lost bone tissue

  - insulin-producing cells to treat diabetes

  -Treatment of bone & blood cancers

  -repair nerve /paralysis/Parkinson's disease

  - Repair of some damaged heart tissue


  Disease possible be helped by stem cells
• Created by iPS (reprogram a somatic cell)

  blastocyts (from extra IVF attempts)


  Source pluripotent Stem cells
• Embryonic


  Which stem cell has the most potential for treating diseases?
• structure that holds embryonic stem cells


  blastocyst inner cell mass