the witches symbolise the supernatural. in the jacobean era, witches were seen as possesed demons, associated with the devil and malovent. anyone associated with witches would be executed
macbeth commiting regicide completely opposes the divine rights of kings. this is where royalty were seen to be chosen by god as well as represent/symbolise god .
shakespeare wrote the play partially due to the intensity of king james beliefs regarding witchcraft and regicide. overall, its belived shakespeare wrote macbeth as a form to flattery to the royalties.