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genetic explanation for schizophrenia
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Anya Dawlatly
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Cards (19)
What does the explanation suggest about the inheritance of schizophrenia?
Schizophrenia
is passed on through our
genes
.
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How does genetic similarity relate to the risk of developing schizophrenia?
The risk of schizophrenia increases with
genetic
similarity
to a
relative
with the condition.
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What was the general population rate of schizophrenia found by Gottesman (1991)?
1%
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What is the chance of developing schizophrenia if someone has an
aunt
with the
condition
?
2%
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What is the chance of developing schizophrenia if someone has a sibling with the condition?
9%
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What is the chance of developing schizophrenia if someone has an identical twin with the condition?
48%
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What do psychologists compare to investigate the genetic links of schizophrenia?
They compare the
concordance rate
of schizophrenia in
identical
and
non-identical
twins.
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What does a higher concordance rate in identical twins suggest about schizophrenia?
It suggests that
genes
play an important role in the development of schizophrenia.
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What does research suggest about the genetic nature of schizophrenia?
Schizophrenia is
polygenic
.
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What did Ripke et al (2014) study reveal about genetic variations related to schizophrenia?
108
genetic variations were found to be associated with an increased risk of schizophrenia.
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What does it mean that schizophrenia is aetiologically heterogeneous?
It means many different combinations of factors, including
genetic variation
, can lead to the condition.
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How can genetic mutations contribute to the development of schizophrenia?
If
parental DNA
mutates, an individual may become genetically predisposed to schizophrenia.
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What correlation exists between paternal age and the risk of schizophrenia?
There is a
positive
correlation between
paternal
age
and the
risk
of
schizophrenia.
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What is the average risk of schizophrenia when a father is under 25 years old?
0.7%
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What is the average risk of schizophrenia when a father is over the age of 50?
2%
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What role do family studies play in understanding the genetic links to schizophrenia?
Family studies confirm that the risk of schizophrenia
increases
with genetic
similarity
.
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Why are concordance rates in twin studies significant for understanding schizophrenia?
They help determine the influence of
genetics
versus
environment
in the disorder's development.
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What are the implications of schizophrenia being polygenic for treatment and research?
It suggests that multiple
genetic factors
need to be considered in treatment and research.
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How does paternal age impact genetic mutations related to schizophrenia?
Older
paternal age is associated with a higher risk of genetic mutations that may lead to schizophrenia.
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