neuro

• What is the dopamine theory related to schizophrenia?

  High dopamine levels correlate with symptoms
• How do drugs that decrease dopamine levels affect schizophrenia?

  They correlate with a reduction in symptoms
• Which substances simulate schizophrenia?

  Cocaine and amphetamines
• What is the role of chlorpromazine in treating schizophrenia?

  It is a dopamine antagonist with antipsychotic effects
• What type of receptors does chlorpromazine bind to?

  Dopamine receptors and other monoamine receptors
• What is the function of haloperidol in schizophrenia treatment?

  It blocks dopamine receptors effectively
• How does haloperidol compare to chlorpromazine?

  Haloperidol has fewer side effects than chlorpromazine
• What did Snyder and colleagues propose about effective antipsychotics?

  They have high affinity for dopamine receptors
• How many types of dopamine receptors are there?

  Five subtypes
• What are the two functional classes of dopamine receptors?

  D1 type and D2 type
• Which dopamine receptors are linked to the activation of adenylyl cyclase?

  D1 and D5 receptors
• Which dopamine receptors are linked to the inhibition of adenylyl cyclase?

  D2, D3, and D4 receptors
• How do antipsychotic drugs mediate their effects?

  By blocking D2 receptors
• What correlates with the effectiveness of antipsychotics?

  Affinity of binding to D2 receptors