Cell mediated response

• What are the two types of lymphocyte?

  B and T
• Where are lymphocytes produced?

  bone marrow
• Is a lymphocyte bigger or smaller than a phagocyte?

  smaller
• Where do T lymphocytes mature?

  in the thymus
• when are T lymphocytes activated?

  when they bind to their specific antigens that are being presented on the membrane
• What do t lymphocytes do once activated?

  they divide by mitosis then differentiate into helper t and cytotoxic t cells
• Examples of antigen presenting cells?

  macrophages, neutrophils
• What do helper t cells do?

  Release cytokine which stimulates the maturation of b cells into plasma cells, memory cells, and cytotoxic t cells
• What do t killer cells do?

  attach to antigens then secrete a toxic substance through holes made by perforins in the membrane
• cell mediated response?

  involves specialised white blood cells called T lymphocytes which target pathogens