Acyl Chlorides and Acid Anhydrides

• Acyl chlorides are like carboxylic acids but have a Cl instead of a OH

  A) Acyl Chloride

  
• Acid Anhydride is a mirror image of itself

  A) Acid anhydride

  
• Acyl Chloride Reactions:

  With H2O forms: Carboxylic acid conditions: room temp Observation = HCl gas producing white steamy fumes

  With OH forms: Ester conditions: room temp observation = HCl gas producing white steamy fumes

  With Ammonia forms: Primary Amide conditions: room temp Observation = NH4Cl White smoke

  With Primary amine forms: Secondary amide conditions: room temp Observation = No observation
• Acid Anhydride reactions:

  With H2O forms carboxylic acid conditions: room temp Observation = no observation

  With OH forms Ester conditions: room temp observation = no observation

  With Ammonia forms Primary Amide conditions: room temp observation = no observation

  With Primary amide forms: Secondary amide conditions: room temp observation = no observation