- multiple births can happen if more than one embryo grows into a baby: risky for both mother and babies (higher risk of miscarriage, stillbirth etc)
- success rate is low (only 26% in the UK) makes the process emotionally stressful and upsetting
- physically stressful for the woman: some have a strong reaction to the hormones (e.g. abdominal pain, vomiting, dehydration)
- expense: each round of IVF and keeping the embryos incubated costs money