Drug therapy

• What is the primary biological treatment for schizophrenia mentioned?

  Antipsychotic drugs
• How do antipsychotic drugs affect dopamine levels?

  They reduce dopamine levels
• What is the role of post-synaptic receptors in dopamine activity?

  They receive dopamine signals
• What happens when there is too much dopamine in the system?

  More positively charged neurons bind to receptors
• What is the effect of antipsychotic drugs on post-synaptic receptors?

  They bind to receptors, reducing neuron activity
• What is the result of reduced activity in the mesolimbic system due to antipsychotic drugs?

  Fewer excitatory post-synaptic potentials (EPSPs)
• What are extrapyramidal symptoms caused by dopamine blocking drugs?

  Muscular spasm, jittery movements
• What are the differences between typical and atypical antipsychotics?

  Typical antipsychotics:

  • Bind to D2 receptors
  • Lead to extrapyramidal symptoms
  • Primarily address positive symptoms

  
  

  Atypical antipsychotics:

  • Lower dopamine neuro blockade
  • Fewer side effects
  • Address both positive and negative symptoms
• What did Leucht contribute to the study of antipsychotics?

  He compared typical and atypical antipsychotics
• How do atypical antipsychotics differ in side effects compared to typical ones?

  Atypical have fewer side effects
• What is the effect of dopamine blocking drugs on every neuron?

  They can worsen symptoms
• What is the primary neurotransmitter affected by antipsychotic drugs?

  Dopamine
• What is the significance of the term "neuro blockade" in the context of atypical antipsychotics?

  It refers to reduced dopamine receptor activity
• How do atypical antipsychotics impact positive symptoms compared to typical ones?

  Atypical reduce positive symptoms more effectively