temperature

• a graph showing how the rate of an enzyme controlled reaction changes with temperature

  
• as the temperature increases so does the rate of reaction because all of the particles will have more kinetic energy so they are more likely to collide and have enough energy to react
• after around 37 degrees the rate starts to drop rapidly this because the hight temperatures start to break apart bonds holding the enzymes together so the active site starts to change shape, if it changes changes shape enough then the enzyme wont be able to bind to the substrate and catalyse the reaction. this calls the enzyme to be denatured
• when the enzyme is denatured the damage caused is permanent, even if you lower the temperature the enzyme wont start working again
• optimum temperature

  the temperature at which the rate of reaction is highest. all enzymes have an optimum temperature but different enzymes have different optimal temperatures