Monitoring + safety netting

• What are some symptoms associated with the RED FLAG COMBO?

  Fever, headache, and altered level of consciousness
• What are additional symptoms that may indicate a serious condition?

  Unwellness, lethargy, and vomiting
• What should be done if a non-blanching rash is present?

  Strongly suspect meningococcal disease
• What antibiotic covers most organisms of interest in meningococcal disease?

  Ceftriaxone
• Which antibiotics are mentioned for empirical treatment?

  Amoxicillin or ampicillin
• What is the recommended dose of ceftriaxone for treatment?

  2 g IV
• Which antibiotics should be monitored for nephrotoxicity?

  Vancomycin and gentamicin
• What physiological parameters should be monitored in confirmed cases?

  Heart rate, blood pressure, and consciousness
• What complications should be considered in patients with renal function issues?

  Possible complications related to renal function
• What is a common side effect of gentamicin?

  Nephrotoxicity
• What can accumulate and damage hair cells when using gentamicin?

  Dry accumulation on the head
• What is a common side effect of antibiotics on the microbiome?

  Dampened microbiome
• What can C. diff infection lead to?

  Life-threatening diarrhea
• What is anaphylaxis mediated by?

  IgE antibodies
• What is the relationship between penicillin allergies?

  If allergic to one, will be allergic to all penicillins and beta-lactams
• What is red man syndrome associated with?

  Fast infusion of vancomycin
• What symptoms can red man syndrome cause?

  Intensely red rash and low blood pressure
• What is neutropenia?

  A decrease in the number of neutrophils
• What can cause agranulocytosis?

  Vancomycin, tazocin, and methotrexate
• What color change can rifampicin cause in urine?

  Orange-red color
• What side effect is associated with doxycycline?

  Photosensitivity and deposition in bones and teeth