Wiles’ study

• What was the aim of this study?

  To test the benefit of using CBT plus antidepressants for treatment-resistant depression, rather than antidepressants alone.
• What was the method of this study?

  Patients with treatment-resistant depression either continued with antidepressant or had CBT as well.

  Improvement measured using Beck’s Depression Inventory (BDI)
• What were the results of this study?

  6 months: 50% reduction in symptoms in 21.6% of usual care group, but 46.1% of usual care group+ CBT

  12 months: usual care + CBT continued to have better recovery.
• What can be concluded from this study?

  Using CBT with antidepressants is more effective than antidepressant medication alone.
• What is a positive evaluation of this study?

  Real-world application.

  The study has led to a useful holistic therapy being developed that helps people with depression.
• What is a negative evaluation of this study?

  Assessment of depression.

  People using self-report methods may not score their depression accurately so results will lack validity.