Phagocytosis

• Where are phagocytes made?

  Bone marrow
• How do phagocytes travel around the body?

  In capillaries
• What is the role of neutrophils?

  They engulf and digest pathogens and dead cells
• What is phagocytosis?

  Non-specific defence where a phagocyte engulfs and destroys pathogens
• What do lysosomes release to digest pathogens during phagocytosis?

  Hydrolytic enzymes
• What forms when a lysosome fuses with a phagosome?

  A phagolysosome
• What happens to the digested pathogen products after phagocytosis?

  They are excreted or used by the phagocyte
• What do phagocytes display after digesting pathogens?

  The antigens from the pathogen
• What is the role of lysosomes in phagocytosis?

  Lysosomes fuse with phagosomes to form phagolysosomes and their lysozymes digest and destroy pathogens
• Describe the process of phagocytosis.

  • The phagocyte engulfs the pathogen
  • Pathogen is contained within a phagosome vesicle
  • A lysosome fuses with the phagosome to form a phagolysosome
  • Lysozyme hydrolyses the pathogen which destroys the pathogen
  • Soluble products are absorbed and used by the phagocyte
• What are phagocytes?

  • Non-specific immune response
  • phagocytes become antigen presenting cells after destroying pathogen