Back pain in association with malignancy is commonly dur to metastasis to the spine (rarely from a primary bone cancer). Cancers more likely to metastasise to the spine:
Breast
Lung
Prostate
Kidney
Thyroid
Myeloma
As cancer that has spread to the spine continues to grow it can damage surrounding structures leading to spinal instability - can lead to spinal cord compression or cauda equina syndrome
Suspect spinal metastases but not MSCC:
Severe unremitting back pain
Progressive back pain
Mechanical pain - aggravated standing, sitting or moving
Back pain aggravated by straining - coughing, sneezing, opening bowels
Night-time back pain disturbing sleep
Localised tenderness
OFFER MRI WITHIN 1 WEEK
Suspect MSCC:
Bladder or bowel dysfunction
Gait disturbance
Limb weakness
Neurological signs of spinal cord or cauda equina compression