Save
...
schizophrenia
schizophrenia - ao1
biological explanations
Save
Share
Learn
Content
Leaderboard
Share
Learn
Created by
Favour Banwo
Visit profile
Cards (21)
What is the genetic explanation for schizophrenia (SZ)?
Individuals inherit a
genetic
vulnerability
View source
What does it mean that SZ is polygenic?
Multiple
genes
are involved affecting
dopamine
View source
How many different genes did Ripke et al find involved in SZ?
108
different genes
View source
What does aetiologically heterogeneous mean in the context of SZ?
Different
combinations
of
factors
can lead to SZ
View source
Can SZ occur without a family history of the disorder?
Yes, due to
radiation
, poison, or
viral infection
View source
How does the risk of developing SZ change with age for men?
Risk triples if over
50
years old
View source
What is the chance of developing SZ if a man is under 25?
0.7%
View source
What is the chance of developing SZ if a man is over 50?
2%
View source
What was the original dopamine hypothesis based on?
Discovery of
antipsychotics
causing
Parkinson's
-like symptoms
View source
How does the original dopamine hypothesis relate schizophrenia to dopamine levels?
Schizophrenia may result from
high dopamine levels
View source
What does 'hyperdopaminergia' mean?
High
levels
of dopamine in the
brain
View source
Which brain area is associated with speech production in schizophrenia?
Broca's area
View source
How might excess dopamine receptors affect speech in schizophrenia?
They may cause
poverty
of speech and hallucinations
View source
Who proposed the updated versions of the dopamine hypothesis?
Kenneth Davis
et al.
View source
What is cortical hypodopaminergia?
Abnormally low dopamine in the
brain's
cortex
View source
How can low dopamine in the prefrontal cortex affect schizophrenia symptoms?
It could explain cognitive problems and
negative symptoms
View source
What relationship is suggested between cortical hypodopaminergia and subcortical hyperdopaminergia?
Cortical hypodopaminergia
leads to
subcortical hyperdopaminergia
View source
What do current versions of the dopamine hypothesis aim to explain?
Links between
abnormal
dopamine levels and
symptoms
View source
What factors contribute to abnormal dopamine function according to current hypotheses?
Genetic
variations
and early stress
experiences
View source
How do early experiences of stress affect dopamine sensitivity?
They make some people
more
sensitive
to
dopamine
changes
View source
What is the significance of Howes et al. (2017) in the context of dopamine hypothesis?
They discussed
stress
and
genetic variations'
effects
View source