Krebs cycle

• Where does the Krebs cycle happen?

  Mitochrondrial matrix
• Describe the Krebs cycle

  • Acetyl fragment from Acetyl CoA combines with oxalacetate to form citrate. CoA detaches
  • Series of redox reactions: Citrate is oxidised and decarboxylated to form a 5 carbon intermediate. The 5 carbon intermediate is decarboxylated and oxidised to form oxalacetate
  • Decarboxylation- decarboxylase removes carbon, produces 2 CO2
  • Oxidisation- Dehydrogenase removes hydrogen, used to produce 2 FADH, 6 NADH.