Neural correlates

• What are neural correlates?

  Patterns of structure/activity in the brain that occur with an experience
• What is the best known neural correlate of schizophrenia?

  Dopamine
• What was the original dopamine hypothesis?

  Hyperdopaminergia in subcortical areas causes schizophrenia
• What is hyperdopaminergia?

  High levels of dopamine
• What is hypodopaminergia?

  Low levels of dopamine
• What may explain auditory hallucinations?

  Hyperdopaminergia in the subcortex to Broca's area
• What was the original dopamine hypothesis based on?

  Antipsychotics caused symptoms similar to Parkinson's disease
• Who proposed cortical hypodopaminergia to the dopamine hypothesis?

  Davis
• How did Davis update the dopamine hypothesis?

  Proposed cortical hypodopaminergia
• What may explain cognitive problems?

  Hypodopaminergia in the prefrontal cortex
• It has been suggested cortical hypodopaminergia leads to subcortical hyperdopaminergia
• Alongside the link between abnormal dopamine levels and symptoms, what do current versions also explain?

  Origins of abnormal dopamine
• What makes some more sensitive to cortical hypodopaminergia?

  Genetic variations and early experiences