Lock and key hypotheses

• What is specifically shaped to fit the substrate?

  The enzyme
• What is the lock and key hypothesis?

  The idea that the active site is specifically shaped to fit the shape of its substrate molecule.
• What does the lock and key hypothesis suggest about how many reactions each type of enzyme can catalyse?

  That each type of enzyme can usually only catalyse only one type of reaction (some may catalyse multiple reactions)
• What happens when an enzyme catalyses a reaction?

  Lock and key hypothesis:

  A)

  B)

  C)

  
• What does it mean if an enzyme denatures?

  When an enzyme changes shape and therefore no longer works