Mutations

• What determines the amino acid sequence of a protein?

  The base sequence of a gene
• What happens to a protein once it is formed?

  It folds into a unique shape
• How does the shape of a protein relate to its function?

  The shape determines the protein's function
• What is a mutation?

  A change to a base in DNA
• Do mutations happen frequently?

  Yes, mutations happen all the time
• What can happen when a single base in DNA changes?

  It may not change the amino acid sequence
• Why might a mutation not affect protein function?

  Different base triplets can code for the same amino acid
• What happens if a mutation alters the shape of a protein?

  It can dramatically affect the protein's function
• What role do non-coding regions of DNA play?

  They switch genes on and off
• What can mutations in non-coding regions lead to?

  Uncontrolled gene expression
• What could uncontrolled gene expression result in?

  Uncontrolled mitosis leading to cancer
• Where can students find more questions on mutations?

  In the revision workbook
• What is the title of the video series this lesson belongs to?

  Three size lessons cold UK
• Who is the intended audience for this video lesson?

  Triple biology higher-tier students