Negative feedback

• Insulin and glucagon control blood glucose levels in the body.
• After a meal, blood glucose levels rise. The pancreas detects this rise. Pancreas secretes insulin which causes liver and muscle cells to increase uptake of glucose. The glucose is stored as glycogen. Blood glucose levels fall back to normal levels.
• After skipping a meal, blood glucose levels decrease. The pancreas detects the fall. Pancreas secretes glucagon which causes liver cells to convert glycogen into glucose and release it into the blood stream. Blood glucose levels fall back into the normal range.