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Jude Brown
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Cards (4)
What is the mechanism of action of metformin?
Lowers blood sugar by reducing
glucose
absorption from the
GI tract
and decreasing
gluconeogenesis
in the liver.
What serious side effect can occur with Metformin, especially in renal failure?
Lactic acidosis
What are the common sulphonylureas used in managing Type Il diabetes?
Glipizide
and
Gliclazide
How do sulphonylureas work in diabetes management?
They stimulate the
pancreas
to produce more
insulin
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