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Semi-conservative DNA replication
Semi conservative dna replication
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DNA Gyrase - relives strain created by helicase unwinding the DNA
DNA
Helicase
- unwinds and separates the double stranded DNA creating a replication fork
Single
stranded
binding
proteins
- prevents separated strands from rebinding
DNA
primase
- generated a short RNA sequence to initiate DNA synthesis
DNA
Primase
III - extends new strands in a 5’ to 3’ direction joining nucleotides together
Okasaki
fragments
- the lagging strand is copied away from the replication fork in short fragments
DNA Polymerase I
- removes RNA primers and replaces them with DNA nucleotides
DNA
Ligase
- joins the Okazaki fragments together with phosphodiester bonds
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