Cell meditated response

• What is the focus of today's video by Miss Astrick?

  The cell mediated response of immunity
• What type of lymphocytes are involved in the specific immune response?

  T lymphocytes
• What is the role of T lymphocytes in the immune response?

  They are involved in the specific immune response
• Where are all lymphocytes made?

  In the bone marrow
• Why are T cells called T cells?

  They mature in the thymus
• What does the cell mediated response involve?

  The response involving T cells
• What is meant by a specific immune response?

  Response to an exact antigen
• What are antigen presenting cells abbreviated as?

  APC
• What is the function of antigen presenting cells?

  They present non-self antigens on their surface
• What types of cells can act as antigen presenting cells?

  Infected body cells, macrophages, and cancer cells
• Why is the response called cell mediated?

  It involves T cells responding to antigens
• What happens after a pathogen is engulfed by phagocytosis?

  Antigens are placed on the surface of the phagocyte
• What type of T lymphocytes have receptors that bind to antigens?

  Helper T cells
• What occurs when helper T cells bind to antigens?

  They become activated and divide by mitosis
• What happens to activated helper T cells after mitosis?

  They differentiate into various cell types
• What can some activated helper T cells stimulate?

  B cells and macrophages
• What are cytotoxic T cells also known as?

  Killer T cells
• What is the function of cytotoxic T cells?

  They destroy abnormal or infected cells
• What protein do cytotoxic T cells release?

  Perforin
• What does perforin do?

  Creates pores in infected cell membranes
• How does perforin lead to cell death?

  It allows substances to enter or leave the cell
• Why do cytotoxic T cells destroy infected cells?

  To prevent viruses from replicating
• What is a common symptom of a viral infection like a cold?

  Sore throat
• Why do you have a sore throat during a cold?

  Cytotoxic T cells destroy infected throat cells
• What is the summary of the cell-mediated response?

  • Involves T lymphocytes responding to antigens
  • Antigen presenting cells include phagocytes and abnormal cells
  • Helper T cells divide and stimulate B cells and macrophages
  • Some become memory cells or cytotoxic T cells
  • Cytotoxic T cells kill infected cells using perforin
• Where can you find practice questions related to this topic?

  Miss Astrick's website
• What should you do if you found the video helpful?

  Give it a thumbs up