Reuptake Mechanism

Created by

Amber Foster

Cards (45)

What happens when a neurotransmitter binds to receptors on the postsynaptic neuron?
It triggers a post-synaptic potential
How do neurotransmitters function in the nervous system?
They transmit signals between neurons across synapses
What is synaptic transmission?
Communication between neurons at a synapse
What is the process of removing neurotransmitters from the synapse called?
Reuptake
What is a synapse?
The gap between two nerve cells
What is the significance of post-synaptic potential in synaptic transmission?
It determines the response of the postsynaptic neuron
What is the synaptic cleft?
It is the gap between two neurons
What is a neurotransmitter?
A chemical released by neurons
What are the components of synaptic transmission?
Release of neurotransmitters from presynaptic terminal
Travel across synaptic cleft
Binding to receptors on postsynaptic membrane
Initiation of response in receiving neuron
What are the steps involved in synaptic transmission?
Neurotransmitter is released from presynaptic neuron
Neurotransmitter travels across the synapse
Binds to receptors on postsynaptic neuron, triggering post-synaptic potential
What is the role of the presynaptic neuron?
It releases neurotransmitters
What are neurotransmitters?
Chemical messengers transmitting signals
What is the function of the presynaptic terminal?
It contains synaptic vesicles for neurotransmitter release
What is the role of the postsynaptic membrane?
It has specialized receptors for neurotransmitters
What is the process called that ends neurotransmitter action in the synapse?
Reuptake
What happens when dopamine is released in the brain?
It binds to receptors, increasing neuron firing
What are the consequences of dopamine not being reuptaken after release?
Excessive activation of dopamine receptors
Potential dysfunction in the nervous system
How does reuptake affect signal transmission in the synapse?
It stops signal transmission and prepares for future messages
Which neurotransmitters use reuptake to end their action?
Serotonin
Dopamine
Norepinephrine
GABA
If reuptake is inhibited, what might be a potential effect on neurotransmitter signaling?
Increased signaling and overstimulation
What is found in the presynaptic terminal?
Synaptic vesicles
What are the three main parts of a synapse?
Presynaptic terminal, synaptic cleft, postsynaptic membrane
What is the primary function of dopamine?
Controls pleasure and reward
What role do transporter proteins play in reuptake?
They remove neurotransmitters from the synapse
How do neurotransmitters function in a synapse?
They travel across the synapse to transmit signals
How does reuptake regulate norepinephrine?
It regulates arousal
How does reuptake affect GABA's function?
It ensures proper inhibition
Why is understanding reuptake important for drug effects?
Helps grasp how antidepressants work
Affects how other drugs influence the nervous system
What condition are SSRIs primarily used to treat?
Depression
What happens to neurotransmitters during reuptake?
They are removed from the synapse
What is the benefit of recycling neurotransmitters through reuptake?
Ensures neurotransmitters are available for transmission
What is the role of reuptake in the nervous system?
Regulating neurotransmitter levels in the synapse
What is GABA's primary function as a neurotransmitter?
It is a major inhibitory neurotransmitter
How do SSRIs affect serotonin levels in the brain?
They prevent serotonin reabsorption, increasing availability.
Why is communication in the nervous system considered efficient due to reuptake?
It maintains balance and availability of neurotransmitters
Why is understanding reuptake important for medication development?
It helps target neurotransmitter systems effectively.
How does reuptake affect dopamine signaling?
It controls signaling through dopamine transporters
How does reuptake prevent overstimulation in the nervous system?
By removing neurotransmitters from the synapse
What role does serotonin play in the body?
Regulates mood, sleep, and appetite
How is excess serotonin managed in the synapse?
Reabsorbed by serotonin transporters