The theme of loneliness is prominent throughout the novel, as many characters experience isolation and longing for companionship.
The theme of friendship is central to the story, as George and Lennie's bond serves as a source of support and comfort in a harsh world.
Loneliness also contributes to the harsh realities of life during the Great Depression, where people were forced to migrate and work hard just to survive.
George and Lennie's relationship highlights the importance of human connection and how it can alleviate feelings of loneliness.
Steinbeck uses vivid imagery and descriptive language to convey the bleakness and hopelessness of their situation.
The use of symbolism, such as the rabbits that Lennie kills, adds depth and complexity to the themes explored in the novel.