Factors that Affect enzymes

• The rate of an enzyme-controlled reaction changes with temperature, increasing as the temperature increases due to more kinetic energy in the particles, and dropping after about 37 degrees as the high temperatures start to break some of the bonds holding the enzymes together and change the shape of the active site.
• The optimum temperature is the temperature at which the rate of reaction is highest, which for most enzymes is 37 degrees.
• All enzymes have an optimal temperature, but different enzymes have different optimal temperatures.
• The rate of reaction can be affected by ph, which is a measure of acidity, with high or low ph lowering the rate of reaction as some of the bonds holding the enzyme together start to break and the active site changes shape.
• The ph at which the enzyme works best is called its optimal ph and it depends on where the enzyme normally works, for example, most enzymes in our body work best at neutral phs of around seven, but the ones that work in the stomach for example have an optimal ph of around two because they need to be able to function in the stomach's acidic environment.