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Neurotransmitters
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The neurotransmitter
glutamate
is the most common
excitatory
transmitter.
GABA
(
gamma-aminobutyric acid
) is the main
inhibitory
neurotransmitter in the central nervous system, helping to reduce
neuronal excitability.
Glutamate
is the main excitatory neurotransmitter in the central nervous system, involved in
learning
,
memory
, and
synaptic plasticity.
GABA
(
gamma-aminobutyric acid
) is the main
inhibitory
neurotransmitter in the central nervous system, involved in reducing
neuronal excitability.
Glutamate
receptors are
ionotropic
or
metabotropic
, with
NMDA
being an example of an
ionotropic
receptor.
NMDA receptors have two binding sites - one for
glutamate
and another for
glycine
/
D-serine.
NMDA
receptors require
co-activation
by
glycine
to open channels that allow
calcium
influx into neurons.
Serotonin
is an important neurotransmitter that regulates
mood
,
appetite
,
sleep
, and other functions.
Norepinephrine is involved in
stress response
,
alertness
, and
memory formation.
Excitatory amino acid transporters
(EAAT) remove excess
glutamate
from
synaptic clefts.
Dopamine
plays a role in
reward
,
motivation
,
movement control
, and
attention.
Serotonin
is involved in
mood regulation
,
sleep
,
appetite
, and
pain perception.
Acetylcholine
is an important neurotransmitter that plays roles in
muscle control
,
attention
, and
cognitive function.
Serotonin
plays a role in
mood regulation
,
sleep
,
appetite control
, and
pain perception.
Dopamine
is associated with
reward
,
motivation
,
pleasure
,
movement
, and
cognition.
Dopamine is involved in
reward pathways
,
motivation
,
movement
, and
cognition.
Norepinephrine/noradrenaline is involved in
stress response
,
attention
, and
alertness.
NMDA
receptors play a role in
long-term potentiation
(LTP), which strengthens
connections
between neurons and underlies
learning
and
memory.
Ion channels
open when both
binding sites
are occupied by their respective
ligands.
Dopamine
is associated with
reward
,
motivation
,
pleasure
,
movement
,
attention
, and
cognition.
Inhibitory amino acids include
GABA
and
glycine.
Inhibitory amino acids include
GABA
and
glycine.
Calcium influx through NMDA receptors can lead to
long-term potentiation
(LTP), which
strengthens
connections between neurons.
Excitatory amino acids include
aspartate
,
glutamate
, and
GABA.
Inhibitory amino acids include
GABA
and
glycine.
Serotonin
plays a role in
mood regulation
,
sleep
,
appetite
, and
pain perception.
Calcium influx through NMDA receptors can lead to
long-term potentiation
(LTP), which
strengthens
connections between neurons.
Calcium influx through NMDA receptors can lead to
long-term potentiation
(LTP), which
strengthens
connections between neurons.
Excitatory amino acids include
aspartate
,
glutamate
, and
GABA.
Serotonin
plays a role in
mood regulation
,
sleep
,
appetite
, and
pain perception.
Serotonin
plays a role in
mood regulation
,
sleep
,
appetite
, and
pain perception.
Serotonin
plays a role in
mood regulation
,
sleep
,
appetite
, and
pain perception.
Acetylcholine
plays a role in
muscle control
,
learning
, and
memory.
Acetylcholine
plays a role in
muscle control
,
learning
, and
memory.
The
serotonergic
pathway involves the release of
serotonin
from
presynaptic
terminals onto
postsynaptic
cells.
The
serotonergic
pathway involves the release of
serotonin
from
presynaptic
terminals onto
postsynaptic
cells.
Excitatory amino acids
like
aspartate
and
glutamate
play important roles in brain function.
Excitatory amino acids
like
aspartate
and
glutamate
play important roles in brain function.
GABA
is the main
inhibitory
neurotransmitter in the
CNS.
GABA
is the main
inhibitory
neurotransmitter in the
CNS.
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