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Neurons + Synaptic Transmission
Structure of Neuron
Myelin Sheath
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Created by
Amber Foster
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Cards (40)
If you wanted to observe the detailed structure of the myelin sheath, which microscope would you use?
Electron microscope
What does the image in the study material illustrate about myelination?
It shows the wrapping process of
Schwann cells
What are the gaps in the myelin sheath called?
Nodes of Ranvier
What are the specialized cells that form myelin in the central nervous system?
Oligodendrocytes
What is the role of the myelin sheath in myelinated axons?
The myelin sheath acts as an
insulator
, allowing for
saltatory conduction
and faster transmission of signals
What is the name of the specialized structure that allows for saltatory conduction in myelinated axons?
Node of Ranvier
What do Schwann cells create during myelination?
The myelin sheath around the
axon
What are the benefits of myelination in neurons?
Increases speed of
impulse transmission
Reduces energy consumption for the neuron
Enhances overall efficiency of neural communication
What are the key functions and characteristics of the myelin sheath?
Fatty layer around
axons
Speeds up
nerve signal transmission
Formed by Schwann cells (PNS) and
oligodendrocytes
(CNS)
Contains gaps called
nodes of Ranvier
Nodes maintain fast signal propagation
How does the transmission speed in myelinated neurons compare to unmyelinated neurons?
Myelinated
neurons
transmit
impulses
faster
What are the specialized support cells that wrap myelin layers in the central nervous system?
Oligodendrocytes
How often do nodes of Ranvier occur along the axon?
Every
1-2 mm
What does the image in the study material illustrate about myelinated axons?
(a) Simplified diagram of myelinated axon
(b) Cross-section showing concentric myelin layers
(c) Light microscopy view of many myelinated axons
(d)
Electron microscopy
view of myelin layers
(e) Fluorescent microscopy showing myelin distribution
What are the steps in the myelination process by Schwann cells?
Schwann cell covers the
axon
Schwann cell wraps around in spirals
Multiple layers accumulate to form myelin
The process leaves a space for the
Node of Ranvier
Why does the voltage decay faster in myelinated axons compared to non-myelinated axons?
Due to the presence of
voltage-gated ion channels
at the
nodes of Ranvier
What are nodes of Ranvier?
Unmyelinated
gaps in the
myelin sheath
How does the myelin sheath affect nerve signal transmission?
It
speeds
up
the
transmission
of
nerve signals
What is the function of the myelin sheath?
It allows for
saltatory conduction
What is the role of the myelin sheath in neuron function?
It speeds up
electrical impulse transmission
What happens to the Schwann cell nucleus during myelination?
It moves to the
side
of the cell
How does the myelin sheath facilitate faster transmission of impulses?
Through
saltatory conduction
along
axons
What is the difference between myelinated and non-myelinated axons in terms of conduction speed?
Myelinated
axons have fast conduction speed (
Fast
)
Non-myelinated
axons have slow conduction speed (
Slow
)
What are the specialized cells that form myelin in the peripheral nervous system?
Schwann cells
How does the voltage-gated ion channel mechanism work in myelinated axons?
Voltage-gated ion channels are present in the bare plasma membrane (
nodes of Ranvier
)
This allows for rapid depolarization and repolarization, resulting in faster conduction speed
How do Schwann cells contribute to the myelination process?
They wrap around the
axon
in multiple layers
What is saltatory conduction in neurons?
Transmission of impulses along
myelinated axons
Impulses jump between
nodes of Ranvier
Results in faster transmission than
unmyelinated neurons
How does the voltage decay differ between myelinated and non-myelinated axons?
In
myelinated
axons, the voltage decays rapidly (Voltage-gated ion channels)
In
non-myelinated
axons, the voltage decays slowly (Slow conduction)
What is wrapped around the axon?
Myelin layers
What is the significance of the layers added by Schwann cells during myelination?
They form the
myelin sheath
for insulation
How do the mechanisms of conduction in myelinated and non-myelinated axons differ?
Myelinated
axons
use saltatory
conduction
via voltage-gated ion channels, while
non-myelinated
axons
use continuous
conduction
How does the speed of saltatory conduction compare to non-myelinated transmission?
It is much faster than non-myelinated transmission
What are the specialized support cells that wrap myelin layers in the peripheral nervous system?
Schwann cells
What is the primary function of the myelin sheath in myelinated axons?
To insulate the axon and allow for faster conduction of
electrical
signals
How does saltatory conduction work?
Electrical impulses jump between
nodes of Ranvier
What is the process of myelination?
Wrapping of
Schwann cells
around an
axon
What is the myelin sheath?
A fatty layer around some
axons
What are the key features of saltatory conduction?
Impulses jump between
nodes of Ranvier
Significantly faster than
non-myelinated
transmission
Prevents signal loss
What is the significance of the nodes of Ranvier?
They help maintain fast
signal propagation
What is left at the end of the myelination process?
A space for the
Node of Ranvier
What role does myelin play in signal loss?
Myelin prevents signal loss during
transmission