midterms pt2

• What type of virus is Poxviridae?

  Enveloped virus
• What is the shape of Poxviridae virions?

  Pleomorphic, brick-shaped or ovoid
• What unique structure covers Poxviridae virions?

  Long thread-like structures in crisscross pattern
• What lesions does Poxviridae cause?

  Pox lesions (pock marks)
• What cells does Poxviridae primarily infect?

  Keratinocytes in skin cells
• Where does Poxviridae replication occur?

  Entirely in cytoplasm within viral factories
• How does Poxviridae survive in dried scabs?

  Resistant to desiccation or drying
• What are Guarnieri bodies?

  Intracytoplasmic inclusion bodies formed by Poxviridae
• What type of immunity does Poxviridae provide?

  Lifelong immunity
• What diagnostic tests are used for Poxviridae?

  PCR, electron microscopy, virus isolation
• How can Poxviridae be isolated and grown?

  In chick embryos and cell cultures
• What type of vaccines are available for Poxviridae?

  Live-attenuated vaccines
• What are the main viruses and diseases associated with Poxviridae?

  • Variola virus
  • Vaccinia virus
  • Myxoma virus
  • Rabbit Fibroma virus
  • Cowpox
  • Bovine papular stomatitis
  • Swinepox
  • Lumpy skin disease
  • Fowlpox virus
  • Orf virus
  • Pseudocowpox
• How is vaccinia virus transmitted?

  Direct contact with infected animals or fomites
• What are the clinical signs of vaccinia virus infection?

  Teat infections in cattle, oral and skin lesions in horses
• What is the pathogenesis of vaccinia virus?

  Enters through skin abrasions, forms papules
• What are the early signs of Myxoma virus infection?

  Blepharoconjunctivitis and swelling of the muzzle
• What is the mortality rate of Myxoma virus in European rabbits?

  99% mortality in infected rabbits
• What are the clinical signs of Rabbit Fibroma virus infection?

  Localized fibromas on the skin
• How is Cowpox transmitted?

  Through direct contact with infected rodents
• What are the clinical signs of Cowpox in humans?

  Single maculopapular skin lesions
• What is the pathogenesis of Bovine papular stomatitis?

  Enters through microabrasions in oral mucosa
• What is the primary vector for Swinepox transmission?

  Pig louse (Haematopinus suis)
• What are the clinical signs of Lumpy skin disease?

  Firm nodules on skin and limb edema
• What is the pathogenesis of Fowlpox virus?

  Localized hyperplasia of the epidermis
• What are the clinical signs of Orf virus infection?

  Lesions at mucocutaneous junctions
• What is the transmission route for Pseudocowpox?

  Milking equipment and cross-suckling
• What is the primary characteristic of Asfarviridae viruses?

  Enveloped, dsDNA viruses
• What is the primary disease caused by Asfarviridae?

  African Swine Fever
• What is the pathogenesis of African Swine Fever?

  Characterized by severe hemorrhagic disease
• What is the primary vector for Iridoviridae viruses?

  Infect arthropods, fish, amphibians, reptiles
• What is the primary disease associated with Adenoviridae?

  Quail Bronchitis Virus
• What are the clinical signs of Egg Drop Syndrome Virus?

  Soft-shelled or shell-less eggs
• What is the pathogenesis of Canine Adenovirus 1?

  Direct contact with infected urine and saliva
• What are the clinical signs of Canine Adenovirus 1 infection?

  Fever, depression, jaundice
• What is the significance of "blue eye" in Canine Adenovirus 1?

  Corneal opacity occurs in 25% of cases
• How long can recovered dogs shed Canine Adenovirus 1?

  Up to 6 months in urine
• What are the main genera of Iridoviridae viruses?

  • Ranavirus
  • Megalocytivirus
  • Lymphocystivirus
• What are the main clinical signs of Quail Bronchitis Virus?

  • Respiratory distress
  • Eye issues (lacrimation, conjunctivitis)
  • High mortality in young quail
• What are the main clinical signs of Egg Drop Syndrome Virus?

  • Soft-shelled, thin-shelled, or shell-less eggs
  • Loss of pigment in pigmented eggs
  • Decrease in egg production