Oral hypoglycemics

• What are the three defects that oral hypoglycemics work on regarding T2DM?


  Insulin resistance, decreased insulin production, increased hepatic glucose production
• Why is Metformin recommended as the first-line medication for T2DM?

  It effectively addresses insulin resistance and glucose production
• What are the main actions of oral hypoglycemics in T2DM?

  • Address insulin resistance
  • Increase insulin production
  • Decrease hepatic glucose production