a new initiative that aims to guide the classification and understanding of mental disorders by revealing the basic processes that give rise to them.The domains investigated are:1. Negative valence2. Positive valence3. Cognitive System4. System for social progress5. Sensorimotor 6. Arousal/regulatory systemThe underlying systems interested involve:genes, molecules, cells, physiology, behaviour, self-report. Hence, people are not grouped by disorders but rather clusters, where clusters are classified in a data-driven manner (e.g. share a same gene)