2nd Generation Cephalosporins

• 2nd-generation cephalosporins are effective against

  • Gram + cocci: S. aureu, S. pneumonia, S. pyogenes, anaerobic streptococci
  • Gram - cocci: N. gonorrhea
  • Gram - rods: E. aerogenes, E. coli, H. influenzae, K. pneumoniae, P. mirabilis
• The suffix "-cef+o/u" is commonly used to indicate 2nd generation cephalosporins.
• 2nd generation cephalosporins include

  • cefoxitin 
  • cefotetan 
  • cefmetazole
• 2nd generation cephalosporins are used in the case of penicillin allergy.