Anti-TB

• Antituberculosis medications are agents used to treat tuberculosis, a disease caused by the bacteria Mycobacterium tuberculosis.
• Antituberculosis medications act mainly by preventing the production of mycolic acid and the synthesis of this cell wall.
• TB therapy is done in two phases.

  1. The initial phase consists of daily doses of isoniazid, rifampin, pyrazinamide, and ethambutol for two months.
  2. only rifampin and isoniazid for four months.
• For HIV-positive patients, the only change that has to be made is to replace rifampin for rifabutin during the whole therapy.