Alcoholic hepatitis

• What is given to manage severe alcoholic hepatitis?

  Prednisolone
• What is alcoholic hepatitis?

  Inflammation and necrosis of liver cells due to long term alcohol use
• What may be seen in alcoholic hepatitis and what are they?

  Mallory bodies - damaged intermediate filaments
• What is perivenular fibrosis in alcoholic hepatitis?

  Scar tissue around central vein
• What stage of alcoholic liver disease is alcoholic hepatitis and is it reversible?

  Stage 2

  Yes with permanent abstinence
• What are some complications of alcoholic hepatitis?

  Cirrhosis

  Liver failure
• What are some features of alcoholic hepatitis?

  Hepatomegaly

  RUQ abdo pain

  Weight loss (gain if portal HTN)
• What are some risk factors for alcoholic hepatitis?

  Female

  Hep C

  Prolonged excessive drinking
• What blood tests are done for alcoholic hepatitis and what is seen?

  FBC (high neutrophils, thrombocytopenia)

  Glucose (low)

  LFTs (AST>ALT, raised ALP and GGT)
• How is alcoholic hepatitis managed?

  Alcohol abstinence

  Corticosteroids