Hodgkin's

• What sex is Hodgkin's lymphoma more common in?

  Males
• What are some RF thought to contribute to Hodgkin's?

  EBV infection

  Immunosuppression

  Autoimmune conditions

  Family history
• What age groups are commonly affected by Hodgkin's?

  20-30

  50+
• How does a patient commonly present with Hodgkin's?

  Lymphadenopathy
• What is a characteristic cell type that is seen in Hodgkin's?

  Reed-Sternberg cell (owl's eye appearance)
• What is the definitive diagnosis for Hodgkin's?

  Lymph node excision biopsy
• What are some blood tests done for Hodgkin's?

  FBC

  LFTs and RFTs

  ESR
• What does the BMJ Best practice recommend for the staging and assessing treatment response of Hodgkin's post chemo?

  PET scans
• What does a Lymph node excision biopsy reveal for Hodgkin's?

  Reed-Sternberg cells
• How is Hodgkin's staged and what does each stage mean?

  1: 1 lymph node region or single extra lymphatic organ or site

  2: 2+ lymph node regions on the same side of the diaphragm

  3: Involves lymph node regions on both sides of the diaphragm

  4: Disseminated involvement of 1+ extra lymphatic organs +/- lymph node involvement
• How is stage 1/2 classical Hodgkin's treated?

  ABVD (chemo) + radiotherapy
• How is stage 3/4 classical Hodgkin's treated?

  Chemotherapy alone