low serotonin in synapse causes problems with mood regulation and may increase anxiety, High Dopamine in synapse causes problems with attention regulation and may explain hyper vigilance, an overactive prefrontal cortex causes an increase in primitive instincts and may explain repetitive, anxiety reducing behaviours which are connected to survival. EG compulsive hand washing as a need to be clean or compulsive checking of locks or light switches as a need to be safe from intruders or electrical fires,