Breast Cancer

• Methods for detection of breast cancer?

  • molecular breast imaging
  • mammoscintigraphy
  • lymphoscintigraphy
  • ultrasound
  • MRI
  • biopsy
• Principle of mammoscintigraphy?

  instead of using a large gamma camera we use small detector as well as a classical X-ray mammography (MG) with which we compare the methods
• what Rf is used in mammoscintigraphy?

  99mTc MIBI (sestamibi) => Maximum activity is in the mitochondria
• Molecular breast imaging (MBI) vs. mammography (MG)

  • Higher sensitivity in MBI
  • Similar specificity in MBI
  • % of “Recall test” was higher in MG
  • True positive biopsies was higher in MBI
  • MBI is recommended in addition to classical MG, particularly in patients at high risk of breast cancer