Peptic ulcer disease

• What are some risk factors for developing peptic ulcers?

  H pylori

  NSAIDs

  SSRIs

  Zollinger Ellison syndrome
• What are some general features of peptic ulcers?

  Epigastric pain

  Nausea
• What is a feature specific to duodenal ulcers?

  Epigastric pain when hungry, but relieved by eating
• What is a feature specific to gastric ulcers?

  Epigastric pain worsened by eating
• What should be tested for when investigating peptic ulcers?

  H pylori
• How should peptic ulcers be managed if H. pylori is negative?

  PPIs until ulcer is healed
• How should peptic ulcers be managed if H. pylori is positive?

  Eradication/ triple therapy should be given
• What does eradication / triple therapy involve for managing H. pylori?

  PPI + 2 antibacterials
• What is the main complication of peptic ulcers?

  Perforation = bleeding