Spinothalamic

Cards (2)

  • What is the function of the spinothalamic tract?
    Pain
    Gross touch
    Temperature
  • Spinothalamic tract.
    Damaged tissue releases prostaglandins → activation of nociceptorstransduction (chemicalelectrical) → AP generated on first-order neuron → travels through dorsal hornsynapse with second-order neuron in dorsal horn (specifically substantia gelatinosa) (1st order releases substance P) → decussation across spinal cordspinothalamic tract (anterolateral) → up to thalamussynapse with third-order neuronprimary somatosensory cortex (post-central gyrus)