How does artheroma cause arthesclerosis?

• Artheroma can cause:

  Heart attack in coronary arteries

  Deep Vien Thrombosis in legs

  Stroke in brain
• Arthesclerosis (caused by artheroma)

  • Hbp + increase in LDL conc
  • Damage to endothelium lining of the arteries
  • Inflammatory response
  • White blood cells migrate to the area
  • Engluf LDL forming foam cells
  • They break down forming fatty streaks on endothelium lining
  • Plaque is formed
  • By build up of LDL, white blood cells and calcium salts
  • Narrows lumen + loses elasticity
  • Restricts blood flow
  • Increasing bp